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Trigeminal Neuralgia, Migraine and Sympathetic Hyperactivity in a Patient With Parry-Romberg Syndrome

MediaScience is the leading provider of lab-based media and advertising research, incorporating a range of neuro-measures including biometrics, facial expression analysis, eye tracking, EEG, and more. With state-of-the-art labs in New York, Chicago, and Austin, MediaScience is discovering actionable insights in advertising, technology, media, and consumer trends.

Dr. Duane Varan, the global authority of neuromarketing research, founded Audience Labs (formerly the Interactive Television Research Institute) during his tenure at Murdoch University in Perth, Australia, in 2001. In 2005, he launched the Beyond : 30 Project, a consortium exploring the changing media and advertising landscape, and in 2008, he was approached by Disney Media Networks to set up a dedicated custom research lab on a broader scale – and so MediaScience was born. Though he officially left Murdoch in 2015, he continues to maintain some research links with the University of South Australia and has been widely recognised for his innovative contributions to teaching and the neuromarketing industry as evidenced by a long list of awards and over 90 published academic papers in his field.

Below is an abstract from a paper that Dr. Varan oversaw about Trigeminal Neuralgia, Migraine and Sympathetic Hyperactivity in a Patient With Parry-Romberg Syndrome from the SAGE Journals.

Abstract:
Parry–Romberg syndrome is a rare disorder of unknown etiology that involves slowly progressive but self-limited wasting of subcutaneous tissues on one side of the face, usually in the distribution of a branch of the trigeminal nerve. In an internet survey of 205 people on the mailing list of the ‘Romberg’s Connection’ site, 52% reported suffering from migraine and 46% from facial pain, almost always affecting the same side as the atrophy. Headaches and facial pain have also featured in case reports, sometimes in association with an intracranial aneurysm or radiological signs of ipsilateral brain pathology.
We had the opportunity to examine trigeminal and cervical sympathetic nerve function in a woman with right-sided Parry–Romberg syndrome, migraine and trigeminal neuralgia. We wished to determine whether signs of trigeminal or cervical sympathetic hyperactivity were associated with the facial hemiatrophy, because aberrant cranial nerve function has been implicated in the pathophysiology of Parry–Romberg syndrome.

Citation:
Drummond P, Hassard S, Finch P. Trigeminal Neuralgia, Migraine and Sympathetic Hyperactivity in a Patient With Parry-Romberg Syndrome. Cephalalgia. 2006;26(9):1146-1149. doi:10.1111/j.1468-2982.2006.01161.x